diff --git a/crates/clawhdf5-format/src/chunked_read.rs b/crates/clawhdf5-format/src/chunked_read.rs
index 70176e2..f9d6567 100644
--- a/crates/clawhdf5-format/src/chunked_read.rs
+++ b/crates/clawhdf5-format/src/chunked_read.rs
@@ -461,6 +461,17 @@ fn collect_chunk_info_inner(
                 file_data[pos + 7],
             ]);
             let offsets = read_key_offsets(file_data, pos, ndims, chunk_dimensions)?;
+            // A chunk's key carries 0 in the element-size dimension. libhdf5
+            // compares that coordinate too when it looks a chunk up
+            // (`H5D__btree_found`), so whether it finds a chunk keyed
+            // otherwise depends on where the key falls; in `cve-2025-44905`
+            // `/Shuffle_float_data_le` (offset 4096) it does not, and h5py
+            // reads fill values there. Such a key is refused here.
+            if chunk_dimensions.is_some() && offsets.last().is_some_and(|&o| o != 0) {
+                return Err(FormatError::ChunkedReadError(format!(
+                    "chunk key {offsets:?} has a non-zero element offset"
+                )));
+            }
             pos += key_size;
 
             // Parse child address
@@ -820,6 +831,47 @@ pub fn list_chunks(
     Ok((chunks, chunk_dims))
 }
 
+/// [`list_chunks`] for reading the chunks through `pipeline`: a dataset
+/// without filters stores every chunk at the chunk's full size, and a chunk
+/// the index records at another size is refused, as libhdf5 refuses it
+/// ("incorrect chunk size returned from index for unfiltered chunk"). Such
+/// a chunk was read at its recorded size, with the rest of the chunk left
+/// as zeros or fill values: `cve-2025-44904`'s `Scale_offset_float_data_le`
+/// has chunks of 38 and 37 bytes for 48-byte chunks, where HDF5 2.0 reads
+/// whatever its buffer held for the missing bytes.
+pub fn list_chunks_for_read(
+    file_data: &[u8],
+    layout: &DataLayout,
+    dataspace: &Dataspace,
+    elem_size: usize,
+    pipeline: Option<&FilterPipeline>,
+    offset_size: u8,
+    length_size: u8,
+) -> Result<(Vec<ChunkInfo>, Vec<usize>), FormatError> {
+    let (chunks, chunk_dims) = list_chunks(
+        file_data,
+        layout,
+        dataspace,
+        elem_size,
+        offset_size,
+        length_size,
+    )?;
+    if pipeline.is_none_or(|p| p.filters.is_empty()) {
+        let chunk_bytes = checked_chunk_byte_len(&chunk_dims, elem_size)?;
+        if let Some(c) = chunks
+            .iter()
+            .find(|c| c.address != u64::MAX && c.chunk_size as usize != chunk_bytes)
+        {
+            return Err(FormatError::ChunkedReadError(format!(
+                "incorrect chunk size returned from index for unfiltered chunk at {:?}: \
+                 {} bytes, expected {chunk_bytes}",
+                c.offsets, c.chunk_size
+            )));
+        }
+    }
+    Ok((chunks, chunk_dims))
+}
+
 pub fn read_chunked_data(
     file_data: &[u8],
     layout: &DataLayout,
@@ -831,11 +883,12 @@ pub fn read_chunked_data(
 ) -> Result<Vec<u8>, FormatError> {
     check_chunk_element_size(layout, datatype, offset_size)?;
     let elem_size = datatype.type_size() as usize;
-    let (chunks, chunk_dims) = list_chunks(
+    let (chunks, chunk_dims) = list_chunks_for_read(
         file_data,
         layout,
         dataspace,
         elem_size,
+        pipeline,
         offset_size,
         length_size,
     )?;
@@ -979,11 +1032,12 @@ pub fn read_chunked_data_cached(
     // lookup is keyed by this dataset's chunk-index address, so another
     // dataset's index or chunks are never used for this read.
     let chunks = cache.chunks_for(addr, rank, || {
-        list_chunks(
+        list_chunks_for_read(
             file_data,
             layout,
             dataspace,
             elem_size,
+            pipeline,
             offset_size,
             length_size,
         )
@@ -1290,11 +1344,12 @@ pub fn read_chunked_data_sweep(
     // lookup is keyed by this dataset's chunk-index address, so another
     // dataset's index or chunks are never used for this read.
     let chunks = cache.chunks_for(addr, rank, || {
-        list_chunks(
+        list_chunks_for_read(
             file_data,
             layout,
             dataspace,
             elem_size,
+            pipeline,
             offset_size,
             length_size,
         )
@@ -1431,11 +1486,12 @@ pub fn read_chunked_data_indexed(
         addr,
         rank,
         || {
-            list_chunks(
+            list_chunks_for_read(
                 file_data,
                 layout,
                 dataspace,
                 elem_size,
+                pipeline,
                 offset_size,
                 length_size,
             )
diff --git a/crates/clawhdf5-format/src/partial_read.rs b/crates/clawhdf5-format/src/partial_read.rs
index 9865c46..b75887c 100644
--- a/crates/clawhdf5-format/src/partial_read.rs
+++ b/crates/clawhdf5-format/src/partial_read.rs
@@ -18,7 +18,7 @@ use alloc::{format, vec, vec::Vec};
 #[cfg(feature = "std")]
 use std::string as alloc_or_std;
 
-use crate::chunked_read::{alloc_output, checked_byte_len, list_chunks};
+use crate::chunked_read::{alloc_output, checked_byte_len, list_chunks_for_read};
 use crate::data_layout::DataLayout;
 use crate::data_read::extract_selection_from_buffer;
 use crate::dataspace::Dataspace;
@@ -294,11 +294,12 @@ pub fn read_selection(
             btree_address: Some(_),
             ..
         } => {
-            let (chunks, chunk_dims) = list_chunks(
+            let (chunks, chunk_dims) = list_chunks_for_read(
                 file_data,
                 layout,
                 dataspace,
                 elem_size,
+                pipeline,
                 offset_size,
                 length_size,
             )?;
diff --git a/crates/clawhdf5/tests/header_validation_interop.rs b/crates/clawhdf5/tests/header_validation_interop.rs
index 74dc419..25614c5 100644
--- a/crates/clawhdf5/tests/header_validation_interop.rs
+++ b/crates/clawhdf5/tests/header_validation_interop.rs
@@ -628,3 +628,47 @@ save("mdc_past_eof", bad)
         "DSET",
     );
 }
+
+/// Chunk index entries HDF5 2.0 mis-reads, refused here. An unfiltered
+/// chunk the index records at less than the chunk's size (`cve-2025-44904`):
+/// HDF5 2.0 fills the rest of the chunk with whatever its buffer held, and
+/// later libhdf5 releases refuse it ("incorrect chunk size returned from
+/// index for unfiltered chunk"); we read the rest as zeros. A chunk keyed
+/// with a non-zero element offset (`cve-2025-44905`): libhdf5's lookup
+/// compares that coordinate too, so whether it finds the chunk depends on
+/// where the key falls (in `cve-2025-44905` it does not, and h5py reads
+/// fill values; in this file it does); we read the chunk.
+#[test]
+fn chunk_index_entries_libhdf5_misreads_are_refused() {
+    skip_if_no_python!();
+    let dir = tempfile::tempdir().unwrap();
+    run_python(
+        dir.path(),
+        r#"
+good = os.path.join(d, "good.h5")
+with h5py.File(good, "w", libver="earliest") as f:
+    f.create_dataset("d", data=np.arange(100, dtype="<i4"), chunks=(37,), fillvalue=-1)
+data = bytearray(open(good, "rb").read())
+tree = data.find(b"TREE")
+while data[tree + 4] != 1:  # the chunk index, not the root group's B-tree
+    tree = data.find(b"TREE", tree + 1)
+assert tree > 0 and data[tree + 5] == 0
+key = tree + 8 + 16  # the first chunk's key: size, filter mask, offsets
+second = key + 24 + 8  # a key (4 + 4 + 2 x 8 bytes), then a child address
+assert struct.unpack_from("<IIQQ", data, second) == (148, 0, 37, 0)
+bad = bytearray(data); struct.pack_into("<I", bad, second, 100)
+open(os.path.join(d, "short_chunk.h5"), "wb").write(bad)
+bad = bytearray(data); struct.pack_into("<Q", bad, second + 16, 4096)
+open(os.path.join(d, "element_offset.h5"), "wb").write(bad)
+"#,
+    );
+    assert_eq!(
+        clawhdf5_reads(&dir.path().join("good.h5"), "d"),
+        Ok(()),
+        "good"
+    );
+    for name in ["short_chunk", "element_offset"] {
+        let err = clawhdf5_reads(&dir.path().join(format!("{name}.h5")), "d").unwrap_err();
+        assert!(err.starts_with("read:"), "{name}: {err}");
+    }
+}